Upregulation of stromal cell derived factor-1α in collagen vascular diseases-associated interstitial pneumonias (CVDs-IPs)
نویسندگان
چکیده
منابع مشابه
Interstitial lung diseases in collagen vascular diseases.
In this review, a clinical update is presented of the most important collagen vascular diseases (CVDs) and the different types of interstitial lung disease (ILD) encountered in these CVDs. These CVDs represent a heterogenous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lungs. The frequency, clinical presentation, prognosis and resp...
متن کاملAbnormal deposition of collagen/elastic vascular fibres and prognostic significance in idiopathic interstitial pneumonias.
BACKGROUND Vascular remodelling has recently been shown to be a promising pathogenetic indicator in idiopathic interstitial pneumonias (IIPs). AIM To validate the importance of the collagen/elastic system in vascular remodelling and to study the relationships between the collagen/elastic system, survival and the major histological patterns of IIPs. METHODS Collagen/elastic system fibres wer...
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OBJECTIVES We investigated the time course of the stromal cell-derived factor 1α (SDF1α) expression and behavior of intravenously administered bone marrow-derived stromal (BMS) cells in the urinary bladder of partial bladder outlet obstruction (PBOO) rats. METHODS Study 1: Recombinant SDF1α or saline was directly injected into the bladder wall of female rats followed by intravenous administra...
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BACKGROUND Hypoxia of the human endometrium is a physiologic event occurring during the perimenstrual period and the local stimulus for angiogenesis. The aim of this study was to investigate the effects of hypoxic stress on the regulation of vascular endothelial growth factor (VEGF) and stromal cell-derived factor-1 (SDF-1/CXCL12), and the potential role of hypoxia-inducible factor-1α (HIF-1α) ...
متن کاملINTERSTITIAL LUNG DISEASE Abnormal deposition of collagen/elastic vascular fibres and prognostic significance in idiopathic interstitial pneumonias
Background: Vascular remodelling has recently been shown to be a promising pathogenetic indicator in idiopathic interstitial pneumonias (IIPs). Aim: To validate the importance of the collagen/elastic system in vascular remodelling and to study the relationships between the collagen/elastic system, survival and the major histological patterns of IIPs. Methods: Collagen/elastic system fibres were...
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ژورنال
عنوان ژورنال: Pulmonary Pharmacology & Therapeutics
سال: 2010
ISSN: 1094-5539
DOI: 10.1016/j.pupt.2009.10.008